Methamphetamine is a powerfully addictive drug that can seriously damage oral health, destroying a person’s smile and natural ability to chew, according to the American Dental Association ADA. More than million Americans have tried methamphetamine also known as meth, crank, crystal and speed , which can be swallowed, injected, snorted or smoked, according to the National Survey on Drug Use and Health. The majority of users range between 18 and 34 years of age. This condition is often called “meth mouth. Brandjord, ADA president. Brandjord explains, “The extensive tooth decay of meth mouth is attributed to the drug’s dry-mouth effect and its propensity to cause cravings for high-calorie carbonated beverages, tooth grinding and clenching, and extended periods of poor oral hygiene. There is no safe level of meth use, but treatment and recovery are possible. Materials provided by American Dental Association.

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I know a guy that lost his front tooth in a bar fight and I could never look at him the same again. Oh man missing a front tooth is kind of a big deal and the fact that he made no mention of it makes me think its a permanent thing. Is it august 5th yet? Ummm a missing front tooth is a deal breaker but maybe it was his test for you or something??

Like maybe it was joke

Season 5 of ‘Black Mirror’ lacks the gut-punch twists of previous seasons, even as its individual episodes are mostly good.

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The How to Train Your Dragon trilogy was nearly a decade in the making. Our handsome boy Hiccup was a quick-study. He and Astrid got together before he Neville Longbottomed. But what for poor, isolated, last-of-his-kind Toothless?

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Metrics details. The gene for odontogenic ameloblast-associated ODAM is a member of the secretory calcium-binding phosphoprotein gene family. ODAM is primarily expressed in dental tissues including the enamel organ and the junctional epithelium, and may also have pleiotropic functions that are unrelated to teeth. Here, we leverage the power of natural selection to test competing hypotheses that ODAM is tooth-specific versus pleiotropic.

We discovered inactivating mutations in all species of placental mammals that either lack teeth or lack enamel on their teeth. A surprising result is that ODAM is also inactivated in a few additional lineages including all toothed whales that were examined. We hypothesize that ODAM inactivation is related to the simplified outer enamel surface of toothed whales. An alternate hypothesis is that ODAM inactivation in toothed whales may be related to altered antimicrobial functions of the junctional epithelium in aquatic habitats.

The secretory calcium-binding phosphoprotein SCPP gene family contains 23 members in the human genome and achieved its present diversity through an extensive series of gene duplication events [ 1 , 2 ]. In mammals, different SCPP genes are expressed in mineralized tissues, mammary glands, and salivary glands [ 2 ].

The gene that encodes odontogenic ameloblast-associated ODAM is a member of the SCPP family and is thought to have originated as far back as the common ancestor of tetrapods and bony fishes more than million years ago [ 2 , 3 , 4 ]. Early in tooth development, ODAM is highly expressed in the enamel organ that gives rise to ameloblasts that produce enamel.

Later in tooth development, ODAM is expressed in the junctional epithelium, which is a specialized epithelium that attaches the soft tissue of the gingiva gums to the enamel surface of the tooth and protects against bacteria that promote periodontal disease [ 5 , 6 , 7 , 8 , 9 ].

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The new site update is up! I think my boyfriend is toothless. There’s a whole list of evidence I’ve assembled in my brain over the last few months that makes me believe he is almost certainly toothless, and I can no longer stand not to know. I’ve decided to try to bring it up this weekend, but I haven’t a clue how. He is obviously very protective of people seeing into his mouth.

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It used to be that watching Black Mirro r required emotional and physical preparation. Whatever Charlie Brooker threw at his audience, there was a virtual guarantee that it would either mess them up mentally or make them want to throw their phones in a garbage disposal. One explores the fascinating potential of virtual reality and explores the limits of marriage, one takes place in a world precisely like our own and grounds its drama in the oversights of Silicon Valley, and the other is a wild, funky romp through the fame machine and its effects.

But each episode leaves viewers with the feeling that the other shoe is still hovering somewhere, waiting eternally to drop. To be fair, technology has changed a lot since the first season of Black Mirror. Its newer seasons have charged on as the horrifying realities of previous episodes played out in real time.

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The first trailer for How to Train Your Dragon 3 — titled The Hidden World — has arrived, giving us the first look at the third and final chapter of the trilogy that has been away for five years. Dean DeBois, who co-wrote and co-directed ‘s How to Train Your Dragon, and wrote and directed its sequel How to Train Your Dragon 2 , returns in those roles for the closing instalment.

Some of his constituents aren’t as pleased though, with the rescued baby dragons from the middle chapter having their way with the food. Everything changes one night, when Hiccup’s dragon friend Toothless comes across another one of his kind: a female, white-skinned dragon called a “Light Fury” by Hiccup’s long-time girlfriend Astrid Hofferson voiced by America Ferrera , as opposed to Toothless being a “Night Fury”.

But as soon as the female dragon catches a glimpse of the humans, she takes off and disappears into a burst of light. The Best Movies on Netflix in India. Though the new trailer doesn’t show that, the premise tells us that Toothless will leave Hiccup and go after the dragon. He’s immediately smitten with her, and even performs a dance for her, like male birds do in our world.

Meanwhile, Hiccup and Astrid discover a hidden dragon world, thus giving us the final chapter of the trilogy its title. Of course, every film needs a villain, and that turns out to be a rival Viking called Gimmel voiced by F. Gimmel somehow captures Toothless’ new dragon friend, and together with Hiccup, Giccup and Co. For the latest videos on gadgets and tech, subscribe to our YouTube channel. Photo Credit: Universal Pictures. Murray Abraham voices the main villain.

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